GLP-1 Cost Calculator

Compare US self-pay list prices for Wegovy, Zepbound, Ozempic, Mounjaro, Saxenda, and Rybelsus on a monthly and annual basis, with insurance and savings programme notes.

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MedicationMonthly (self-pay)Annual (self-pay)With insurance

Wegovy

semaglutide 2.4 mg

Weight
$1,349$16,188With insurance: ~$0–$50/mo if covered for obesity; many plans exclude obesity drugs

Zepbound

tirzepatide 5–15 mg

Weight
$1,059$12,708With insurance: ~$0–$50/mo if covered; use LillyDirect for ~$550/mo self-pay

Mounjaro

tirzepatide 5–15 mg

Diabetes
$1,023$12,276With insurance: typically covered for T2D; obesity coverage varies widely

Ozempic

semaglutide 0.5–2 mg

Diabetes
$969$11,628With insurance: commonly covered for T2D; may require prior authorisation

Saxenda

liraglutide 3 mg

Weight
$1,395$16,740With insurance: varies; many plans require prior authorisation for obesity

Rybelsus

oral semaglutide 14 mg

Diabetes
$935$11,220With insurance: typically covered for T2D; oral form may have lower copay

Manufacturer savings programmes

Wegovy

Novo Nordisk offers a savings card; eligible patients may pay as little as $0/month.

Zepbound

Lilly offers a savings card for eligible commercially-insured patients.

Mounjaro

Lilly insulin value programme available for eligible patients.

Ozempic

Novo Nordisk offers a savings card for eligible patients.

Saxenda

Novo Nordisk offers a co-pay assistance programme for eligible patients.

Rybelsus

Novo Nordisk offers savings cards; check NovoCare for eligibility.

Pricing disclaimer Prices are US list (WAC) prices as of early 2025 and are approximate. Actual costs vary widely based on insurance coverage, pharmacy, manufacturer savings programmes, and compounding pharmacy alternatives (which are not FDA-approved). Always verify current pricing with your pharmacy. This tool is for informational purposes only and does not constitute financial or medical advice.

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GLP-1 Cost

GLP-1 Cost Calculator — Wegovy, Zepbound, Ozempic monthly and annual cost

GLP-1 weight-loss medications are among the most expensive treatments in the US, with self-pay list prices ranging from ~$935 to ~$1,395 per month. This GLP-1 cost calculator compares monthly and annual self-pay costs for Wegovy, Zepbound, Ozempic, Mounjaro, Saxenda, and Rybelsus, with insurance and savings programme notes.

How much does Wegovy or Ozempic cost per month?

US list (WAC) prices as of early 2025: Wegovy (Novo Nordisk) ~$1,349/month; Zepbound (Eli Lilly) ~$1,059/month; Ozempic ~$936/month; Mounjaro ~$1,069/month; Saxenda ~$1,349/month; Rybelsus ~$935/month. These are approximate pre-coupon list prices without insurance.

Actual out-of-pocket costs vary enormously based on insurance coverage. Many US commercial plans cover Ozempic and Mounjaro for type 2 diabetes with standard copays. Coverage for the weight-management brands (Wegovy, Zepbound, Saxenda) is far less consistent — the Consolidated Appropriations Act of 2023 excluded these drugs from Medicare Part D coverage.

Manufacturer savings programmes and compounding alternatives

Both Novo Nordisk and Eli Lilly offer savings cards that can reduce self-pay costs to $0–$25/month for eligible commercially-insured patients, and Lilly's LillyDirect programme offers Zepbound at ~$550/month for self-pay patients. These programmes change frequently — check manufacturer websites for current eligibility.

Compounded semaglutide became widely available during FDA drug shortages (2022–2024) at a fraction of brand prices. The FDA requires compounded medications to be discontinued when the branded drug is no longer in shortage. Compounded GLP-1s are not FDA-approved and carry different safety, purity, and dosing considerations.

Frequently asked questions

Does insurance cover Wegovy or Zepbound?

Coverage varies widely. Medicare Part D is prohibited from covering weight-loss drugs under current law (though legislation to change this has been proposed). Many commercial plans exclude obesity pharmacotherapy or require prior authorisation. Check your plan's formulary; some employers are beginning to add GLP-1 coverage.

 Is there a cheaper alternative to Wegovy?

Ozempic (same molecule as Wegovy at lower dose) is often more accessible through insurance for type 2 diabetes. During shortages, compounded semaglutide was significantly cheaper, though it is not FDA-approved and carries different risks. Saxenda is the oldest GLP-1 for weight loss and may have more consistent insurance coverage on some plans.

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GLP-1 Medication Comparison Calculator

Compare Wegovy, Zepbound, Ozempic, Mounjaro, Saxenda, and Rybelsus side-by-side on weight loss outcomes, administration, half-life, mechanism, and approval status.

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GLP-1 Eligibility Calculator

Check whether your BMI and health conditions meet FDA label criteria for GLP-1 weight-loss medications such as Wegovy, Zepbound, and Saxenda.

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GLP-1 Weight Loss Calculator

Project expected weight loss on Wegovy, Zepbound, Ozempic, Saxenda, or Mounjaro from your starting weight, based on pivotal clinical trial averages at 3, 6, 12, and 18 months.

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GLP-1 Dose Schedule Calculator

Generate a personalised GLP-1 titration schedule with dated dose phases for Wegovy, Zepbound, Ozempic, Saxenda, or other medications from your first injection date.

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