GLP-1 Dose Schedule Calculator

Generate a personalised GLP-1 titration schedule with dated dose phases for Wegovy, Zepbound, Ozempic, Saxenda, or other medications from your first injection date.

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Wegovy

Medication

5

Dose phases

Sundays

Injection day

PhaseDoseStartEndDuration
10.25 mg 15 March 202612 April 20264 weeks
20.5 mg 12 April 202610 May 20264 weeks
31 mg 10 May 20267 June 20264 weeks
41.7 mg 7 June 20265 July 20264 weeks
52.4 mg (maintenance) 5 July 2026—Ongoing
Maintenance dose: 2.4 mg (maintenance) Titration schedules are general guidance only. Your clinician may adjust the pace based on tolerability and response. Never skip doses or escalate faster than instructed.

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GLP-1 Titration Schedule

GLP-1 Dose Schedule Calculator — Wegovy, Ozempic, Zepbound titration schedule

GLP-1 medications use a gradual dose escalation (titration) to minimise nausea and gastrointestinal side effects. This GLP-1 dose schedule calculator generates a personalised titration schedule with dated phases for Wegovy, Zepbound, Ozempic, Mounjaro, Saxenda, or Rybelsus from your first injection date.

Why GLP-1 medications require titration

Starting at the full maintenance dose causes high rates of nausea, vomiting, and GI discomfort. Titration protocols begin at a sub-therapeutic dose and increase every 4–8 weeks, allowing the body to adapt. For Wegovy, the titration process takes 16 weeks to reach the 2.4 mg maintenance dose from the 0.25 mg starting dose.

Clinicians may slow titration further if side effects are troublesome — remaining at a lower dose for an extra 4 weeks is common. The schedule shown here reflects the standard manufacturer titration; your clinician's guidance takes precedence.

Wegovy titration schedule

Wegovy (semaglutide 2.4 mg) escalates over five phases: 0.25 mg (weeks 1–4) → 0.5 mg (weeks 5–8) → 1 mg (weeks 9–12) → 1.7 mg (weeks 13–16) → 2.4 mg maintenance (week 17+). Each phase lasts four weeks.

Zepbound (tirzepatide) uses a longer titration with up to six phases reaching 15 mg: 2.5 mg → 5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg. Many patients reach an effective maintenance dose before the maximum.

Frequently asked questions

Can I speed up my GLP-1 titration?

No — do not escalate faster than your prescribed schedule without clinician guidance. Faster escalation significantly increases GI side effects. Some patients tolerate slower titration and stay at a lower dose longer.

 What day of the week should I inject Wegovy or Ozempic?

You choose your injection day and keep it consistent each week. The calculator shows your injection day based on the start date you enter. You can change injection day by shifting to a new day with no more than a 3-day gap from the last injection.

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